Due to its relatively high incidence (about 44.69%) in encephaloma and its poor prognosis, cerebral glioma has become a tumor extremely difficult to be cured, with an average survival of less than one year :
It grows in infiltrative pattern, difficult for resection, and high postoperative recurrence.
A majority of cerebral gliomas are not sensitive to radiotherapy and chemotherapy.
Stereotaxy-Guided Cryoablation
As an ancillary means of brain surgery, stereotaxy-guided cryoablation has the advantage of accurate localization and is less traumatic, less hemorrhagic, safe and convenient to perform. Furthermore, ablated tumor tissue remnants can activate immunoreactions.
Percutenous Cryoablation of Cerebral Glioma
Case 3*. Right temporal glioma, astrocytoma (grade II) recurrent six months after glioma surgery. Stereotaxy-guided
percutaneous cryoablation was performed plus intravenous protocol and local anesthesia, tumor center as the target, 3mm-diameter cryoprobe, and an ice ball of 5cm diameter as shown by CT, covered the tumor entirely. The patient was discharged one week after the surgery.
CT re-examination two weeks later showed that the tumors was mostly necrotized and absorbed; the patient had no particular discomfort and she became completely independent. During the five year follow-up, no recurrence had been found in this patient. |
